|
Largactil ( Thorazine, Generic Chlorpromazine ) - Product Origin: New Zealand |
| Manufacturer: | Sanofi Aventis manufactures Largactil ( Thorazine, Generic Chlorpromazine ) - Product Origin: New Zealand. |
| Uses: | The uses of Largactil ( Thorazine, Generic Chlorpromazine ) - Product Origin: New Zealand include:
LARGACTIL is indicated in the following conditions:
1.Schizophrenia and other psychoses (especially paranoid),
mania and hypomania.
2.In anxiety psychomotor agitation excitement, violent or
dangerously impulsive behaviour. LARGACTIL is used as an
adjunct in the short-term management of these conditions.
3.Intractable hiccup.
4.Nausea and vomiting of terminal illness (where other
medicines have failed or are not available).
5.Induction of hypothermia is facilitated by LARGACTIL which
prevents shivering and causes vasodilation.
6.Childhood schizophrenia and autism.
Dosage and Administration
Oral administration should be used whenever possible. Dosages should be low to begin with and gradually increase under close supervision until the optimum dosage within the recommended range for the individual is reached. Individuals vary considerably and the optimum dose may be affected by the formulation used.
The parenteral formulation may be used in emergencies. It may only be administered by deep intramuscular injection. LARGACTIL is too irritant to give subcutaneously. Repeated injections should be avoided if possible.
Schizophrenia, Psychoses, Anxiety and Agitation
Oral
Adult
Initially 25 mg three times daily or 75 mg at bedtime increasing by daily amounts of 25 mg to an effective maintenance dose. This is usually in the range 75 to 300 mg daily, but some patients may require up to 1 g daily.
Children
Under 1 Year: Do not use unless need is life saving.
1-5 Years: 0.5 mg/kg bodyweight every 4 - 6 hours to a maximum recommended dose of 40 mg daily.
6 -12 Years: A third to half the adult dose, to a maximum recommended dose of 75 mg daily.
Elderly
Start with a third to a half the usual adult dose with a more gradual increase in dosage.
Intramuscular
Adult
For acute relief of symptoms 25 - 50 mg every 6 - 8hours.
Children
Under 1 Year: Do not use unless need is life saving.
1-5 Years: 0.5 mg/kg bodyweight every 6 - 8 hours. Dosage is not advised to exceed 40 mg daily.
6-12 Years: 0.5 mg/kg bodyweight every 6 - 8 hours. Not to exceed 75 mg daily.
Elderly
Doses in the lower range for adults should be sufficient to control symptoms, i.e. 25 mg, 8 hourly.
Intractable Hiccup
Oral
Adult
25 - 50 mg three or four times daily.
Children
No information available.
Elderly
No information available.
Intramuscular
Adult
25 - 50 mg every 6-8 hours. .
Children
No information available.
Elderly
No information available
Intravenous Infusion
Adult
If other routes of administration are inappropriate, give 25-50 mg in 500-1000 ml sodium chloride by slow intravenous infusion every 6-8 hours.
Children
No information available.
Elderly
No information available.
Induction of hypothermia to prevent shivering
Intramuscular
Adult
25 - 50 mg every 6 - 8 hours.
Children
Under 1 Year: Do not use in children this age.
1-12 Years: Initial dose: 0.5 - 1.0 mg/kg. Maintenance: 0.5 mg/kg every 4 - 6 hours.
Elderly
No information available.
Nausea and Vomiting of Terminal Illness
Oral
Adults
10 - 25 mg every 4 - 6 hours.
Children
Under 1 Year: Do not use unless need is life saving.
1-5 Years; 0.5 mg/kg every 4 - 6 hours. Maximum daily dosage should not exceed 40 mg.
6 - 12 Years: 0.5 mg/kg every 4 - 6 hours. Maximum daily dosage should not exceed 75 mg.
Elderly
Initially a third to half the adult dose. The physician should then use their clinical judgement to obtain control.
Intramuscular
Adults
25 mg initially, then 25 - 50 mg every 3 - 4 hours until vomiting stops, then drug to be taken orally.
Children
Under 1 Year: Do not use unless need is life saving.
1 - 5 Years: 0.5 mg/kg 6 - 8 hourly. It is advised that maximum daily dosage should not exceed 40 mg.
6-12 Years: 0.5 mg/kg every 6 - 8 hours. It is advised that maximum daily dosage should not exceed 75 mg.
Elderly
For oral use only.
|
<a href=http://www.freedom-pharmacy.com/BannerAdClicks.asp?AdID=2&AffID=789&Page=Products2.asp?Brand=&T=&ID=5533></a>
 |
 |
|
|